tag:blogger.com,1999:blog-717602462727821401.post8579865884036182953..comments2023-10-10T04:45:03.155-04:00Comments on Colgate Virology (and Immunology) Blog: Bacterial Infection? ...Have a dose of virus.Geoffhttp://www.blogger.com/profile/07472521875173404609noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-717602462727821401.post-47918746020905864222015-03-19T08:35:15.693-04:002015-03-19T08:35:15.693-04:00Thanks for sharing this interesting blog with us. ...Thanks for sharing this interesting blog with us. My pleasure to being here on your blog..I wanna come back here for new post from your site.<br /><br /><a href="http://www.pharmaonlinerx.com/mens-health/40-generic-cialis-softgel.html" rel="nofollow">Cialis SoftGel<br /></a><br /><br />Anonymoushttps://www.blogger.com/profile/09795570403698644293noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-80128274207740679122013-09-20T09:54:12.990-04:002013-09-20T09:54:12.990-04:00Thanks for giving nice information regarding antib...Thanks for giving nice information regarding antibiotics work, here i have added the information which i got from some other website <a href="http://www.pharmacy-international-direct.com/antiboitics.php" rel="nofollow">antibiotics to buy</a>. It would be more helpful if it contains treatment tips.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-39819345216268572862013-04-08T00:27:45.014-04:002013-04-08T00:27:45.014-04:00An example of this type of combination treatment w...An example of this type of combination treatment was demonstrated by Zhang and Buckling in their recent article, "Phages limit the evolution of bacterial antibiotic resistance in experimental microcosms." They showed that while antibiotics killed more of the bacteria in infected cells, the resistant mutants showed little or no decrease in fitness. Conversely, when exposed solely to phages, the bacteria quickly evolved resistance, but showed a much greater decrease in fitness. In combination, these two therapies drove 23 of 24 bacterial populations to extinction, and the one that evolved resistance showed significantly reduced levels of fitness. These results are very promising and will hopefully yield similar findings in animal models. Additionally, the efficacy of these combination treatments will continue to improve with the discovery of more effective phages by scientists such as Kęsik-Szeloch and others.<br /><br />Zhang, Quan-Guo and Angus Buckling. "Phages limit the evolution of bacterial antibiotic resistance in experimental microcosms." Evol Appl. 2012 September; 5(6): 575–582. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461140/Evan Angelushttps://www.blogger.com/profile/13493128228665921172noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-23952485490877502062013-04-05T08:27:11.426-04:002013-04-05T08:27:11.426-04:00Resistance is a problem for any new therapy. I thi...Resistance is a problem for any new therapy. I think we'll have to go to a "cocktail" phage system like the HAART therapy in use for HIV-1 infection...resistance to any one drug/treatment is fairly easy to generate, but generating resistance to multiple modalities at the same time is very difficult, especially if (as is the case with HAART) deriving resistance to one of the treatments makes the microbe more susceptible to the others.Geoffhttps://www.blogger.com/profile/07472521875173404609noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-69958339992232011652013-04-04T23:57:22.974-04:002013-04-04T23:57:22.974-04:00This is a valid point, but while I highlighted ant...This is a valid point, but while I highlighted antibiotic resistant bacteria in hospitals in this blog post, they can still be found in many other environments. Unfortunately, they are rather common in poor prison systems, where there is not much hope for a "clean-up" project. Creating a cheap and efficient alternative to antibiotics would be a huge stride forward in helping many people, especially in areas where preventative measures are difficult to put in place due to poor infrastructure.Evan Angelushttps://www.blogger.com/profile/13493128228665921172noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-72267632412347651852013-04-04T23:49:56.554-04:002013-04-04T23:49:56.554-04:00The problem I foresee with this approach is that b...The problem I foresee with this approach is that bacteria can simply evolve to become resistant to bacteriophages just as they have already become resistant to a broad range of antibiotics. Using bacteriophages is a short term solution rather than something long term, like improving hospital sanitation techniques. alterodenthttps://www.blogger.com/profile/17637926518112233688noreply@blogger.com