tag:blogger.com,1999:blog-717602462727821401.post7705202804621080428..comments2023-10-10T04:45:03.155-04:00Comments on Colgate Virology (and Immunology) Blog: Not a Crazy Idea: TLRs Implicated in Psychiatric DisordersGeoffhttp://www.blogger.com/profile/07472521875173404609noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-717602462727821401.post-69182793284436287362011-12-27T23:51:04.165-05:002011-12-27T23:51:04.165-05:00Hello,
Thank you for sharing such relevant topic ...Hello,<br /><br />Thank you for sharing such relevant topic with us. Toll-like receptors play a crucial role in the recognition of invading pathogens and the activation of subsequent immune responses against them, which is generally involved in the defense against microbial infections...<br /><br /><a href="http://imgenex.com/antibody_list.php?id=119&done=null" rel="nofollow">Innate Immunity</a>Drug Discoveryhttps://www.blogger.com/profile/11941871784514986251noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-63280896926534800852011-09-10T20:58:59.854-04:002011-09-10T20:58:59.854-04:00It's most likely a manifestation of an underly...It's most likely a manifestation of an underlying problem. However, if prenatal viral hypotheses are correct then the TLR disruption may be an upstream factor. For instance, cytokines produced in utero may cross into the brain, cause inflammation, and hinder the migration and further development of neurons. After birth, this may lead to the compromised structure of, amongst other areas, the prefrontal cortex and produce some of the common positive and negative symptoms seen in Schizophrenia.Hanna Algattashttps://www.blogger.com/profile/03230577617508667927noreply@blogger.comtag:blogger.com,1999:blog-717602462727821401.post-31464245327808485222011-09-07T23:59:33.405-04:002011-09-07T23:59:33.405-04:00Thanks for the post! Not an area I'm really fa...Thanks for the post! Not an area I'm really familiar with. One thing to think about with these types of studies is correlation vs. causation. Is there evidence to think that these TLR-mediated effects might be a cause of the condition, or just a manifestation of some other underlying problem related to the psychiatric condition?Geoffhttps://www.blogger.com/profile/07472521875173404609noreply@blogger.com